Heart failure is an increasing concern to public health, affecting approximately 5.1 million Americans and costing the United States over $32 billion annually. Compounding the concern, recent research into the quality and efficiency of healthcare has exposed a significant problem of hospital readmissions for the heart failure population, with an estimated 25% of heart failure patients rehospitalized within 30 days of discharge. This project focuses on an education-based strategy designed to decrease hospital readmissions for this at-risk population. In particular, an interprofessional outpatient educational program (Heart Failure University) was initiated in 2013 to reduce healthcare costs and increase the quality of care for heart failure patients at a large private hospital in Northeast Florida. A retrospective case control study was conducted to compare 30-day hospital readmissions of patients who attended Heart Failure University to patients who received standard education. Results indicated a significant association between Heart Failure University attendance and reduced 30-day hospital readmissions for heart failure patients. These findings corroborate with current research on transitional care interventions and emphasize the importance of interprofessional, educational-based disease management programs for the heart failure population.